[HTML][HTML] Sensitive and specific multi-cancer detection and localization using methylation signatures in cell-free DNA
…, X Wang, DP Cosgrove, NR Abu-Rustum, J Trent… - Annals of …, 2020 - Elsevier
Background Early cancer detection could identify tumors at a time when outcomes are
superior and treatment is less morbid. This prospective case-control sub-study (from …
superior and treatment is less morbid. This prospective case-control sub-study (from …
NCCN Task Force report: update on the management of patients with gastrointestinal stromal tumors
…, RF Riedel, S Schuetze, HM Sundar, JC Trent… - Journal of the National …, 2010 - jnccn.org
Background Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal
tumors of the gastrointestinal tract. Neoplastic GIST cells seem to arise from a common …
tumors of the gastrointestinal tract. Neoplastic GIST cells seem to arise from a common …
Not so crystal clear: the structure of the human telomere G-quadruplex in solution differs from that present in a crystal
J Li, JJ Correia, L Wang, JO Trent… - Nucleic acids …, 2005 - academic.oup.com
The structure of human telomere DNA is of intense interest because of its role in the biology
of both cancer and aging. The sequence [5′-AGGG(TTAGGG) 3 ] has been used as a …
of both cancer and aging. The sequence [5′-AGGG(TTAGGG) 3 ] has been used as a …
Ordered nanoparticle arrays formed on engineered chaperonin protein templates
…, J Howard, SL Chan, NJ Zaluzec, JD Trent - Nature materials, 2002 - nature.com
Traditional methods for fabricating nanoscale arrays are usually based on lithographic
techniques. Alternative new approaches rely on the use of nanoscale templates made of synthetic …
techniques. Alternative new approaches rely on the use of nanoscale templates made of synthetic …
G‐quadruplex secondary structure obtained from circular dichroism spectroscopy
R del Villar‐Guerra, JO Trent… - Angewandte Chemie, 2018 - Wiley Online Library
A curated library of circular dichroism spectra of 23 G‐quadruplexes of known structure was
built and analyzed. The goal of this study was to use this reference library to develop an …
built and analyzed. The goal of this study was to use this reference library to develop an …
Marine snow: sinking rates and potential role in vertical flux
AL Shanks, JD Trent - Deep Sea Research Part A. Oceanographic …, 1980 - Elsevier
The sinking rate of intact marine snow (macroscopic aggregates) was determined in settling
chambers on seven occasions in Monterey Bay, California and in the northeastern Atlantic. …
chambers on seven occasions in Monterey Bay, California and in the northeastern Atlantic. …
A missense mutation in KIT kinase domain 1 correlates with imatinib resistance in gastrointestinal stromal tumors
LL Chen, JC Trent, EF Wu, GN Fuller, L Ramdas… - Cancer research, 2004 - AACR
KIT gain of function mutations play an important role in the pathogenesis of gastrointestinal
stromal tumors (GISTs). Imatinib is a selective tyrosine kinase inhibitor of ABL, platelet-…
stromal tumors (GISTs). Imatinib is a selective tyrosine kinase inhibitor of ABL, platelet-…
Molecular subtypes of KIT/PDGFRA wild-type gastrointestinal stromal tumors: a report from the National Institutes of Health Gastrointestinal Stromal Tumor Clinic
…, MP LaQuaglia, CB Weldon, S George, JC Trent… - JAMA …, 2016 - jamanetwork.com
Importance Wild-type (WT) gastrointestinal stromal tumors (GISTs), which lackKITandPDGFRAgene
mutations, are the primary form of GIST in children and occasionally occur in adults. …
mutations, are the primary form of GIST in children and occasionally occur in adults. …
Avapritinib in advanced PDGFRA D842V-mutant gastrointestinal stromal tumour (NAVIGATOR): a multicentre, open-label, phase 1 trial
…, WD Tap, P Rutkowski, SP Chawla, J Trent… - The Lancet …, 2020 - thelancet.com
Background Targeting of KIT and PDGFRA with imatinib revolutionised treatment in
gastrointestinal stromal tumour; however, PDGFRA Asp842Val (D842V)-mutated gastrointestinal …
gastrointestinal stromal tumour; however, PDGFRA Asp842Val (D842V)-mutated gastrointestinal …
Axitinib plus pembrolizumab in patients with advanced sarcomas including alveolar soft-part sarcoma: a single-centre, single-arm, phase 2 trial
Background VEGF promotes an immunosuppressive microenvironment and contributes to
immune checkpoint inhibitor resistance in cancer. We aimed to assess the activity of the VEGF …
immune checkpoint inhibitor resistance in cancer. We aimed to assess the activity of the VEGF …
