Dysregulation of miRNA expression has been implicated in cancer. Numerous strategies
have been explored to modulate miR but sub-optimal delivery and inability to concurrently …

COVID-19 is a pneumonia-like disease with highly transmittable and pathogenic properties
caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which infects …

Cluster of differentiation 147 (CD147) or extracellular matrix metalloproteinase inducer (EMMPRIN)
is a transmembrane glycoprotein that induces the synthesis of matrix …

Circular RNAs (circRNAs) are a novel class of non-coding RNAs. They are single-stranded
RNA transcripts characterized with a closed loop structure making them resistant to …

The increasing incidence of various cancers indicates the urgent need for finding accurate
early diagnostic markers and more effective treatments for these malignancies. MicroRNAs (…

Aims In this research, ferutinin was evaluated for its possible cytotoxic and apoptotic inducing
effects in vitro and in vivo. Main methods To determine IC 50 values of ferutinin, CT26, …

MicroRNAs (miRNAs) are a class of endogenously expressed non-coding regulators of the
genome with an ability to mediate a variety of biological and pathological processes. There is …

A current hurdle in cancer management is the intrinsic or acquired resistance of cancer cells
to chemical agents that restricts the efficacy of therapeutic strategies. Accordingly, there is …

Conclusions TILAM is activated in HSCs with liver injury and interacts with PML to drive the
development of fibrosis. Depletion of TILAM may serve as a therapeutic approach to combat …

Colorectal cancer (CRC) is the second leading cause of cancer-related mortality worldwide.
The disease still remains incurable and highly lethal in the advanced stage, representing a …