Surgical management of the axilla in clinically node-positive breast cancer patients converting to clinical node negativity through neoadjuvant chemotherapy: current …

…, G Kadayaprath, L Dostalek, H Nina, P Krivorotko… - Cancers, 2021 - mdpi.com
Simple Summary Currently, it is unclear which kind of axillary staging surgery breast cancer
patients with lymph node metastasis should receive after neoadjuvant chemotherapy. For …

[HTML][HTML] Capivasertib in hormone receptor–positive advanced breast cancer

…, X Hu, K Jhaveri, P Krivorotko… - … England Journal of …, 2023 - Mass Medical Soc
Background AKT pathway activation is implicated in endocrine-therapy resistance. Data on
the efficacy and safety of the AKT inhibitor capivasertib, as an addition to fulvestrant therapy, …

[HTML][HTML] Immunology and immunotherapy in breast cancer

…, A Artemyeva, P Krivorotko… - Cancer biology & …, 2022 - ncbi.nlm.nih.gov
Immuno-oncology is a rapidly developing field in medicine. Drug combination therapies
have already been studied in many clinical trials on various tumor types. In recent years, a …

PF-05280014 (a trastuzumab biosimilar) plus paclitaxel compared with reference trastuzumab plus paclitaxel for HER2-positive metastatic breast cancer: a …

…, S Hingmire, H Iwase, PV Krivorotko… - British Journal of …, 2019 - nature.com
Background This randomised, double-blind study compared PF-05280014 (a trastuzumab
biosimilar) with reference trastuzumab (Herceptin®) sourced from the European Union (…

Frequency and spectrum of founder and non-founder BRCA1 and BRCA2 mutations in a large series of Russian breast cancer and ovarian cancer patients

…, IV Bizin, IA Stepanov, PV Krivorotko… - Breast Cancer Research …, 2020 - Springer
Background The spectrum of BRCA1 and BRCA2 mutations in Slavic countries is characterized
by a high prevalence of founder alleles. Methods We analyzed a large data set of …

Quantification of linear and nonlinear elasticity by compression optical coherence elastography for determining lymph node status in breast cancer

…, AY Vorontsov, PV Krivorotko… - Laser Physics …, 2023 - iopscience.iop.org
We report the first application of compression optical coherence elastography (C-OCE) to
evaluate both linear and nonlinear elastic properties of lymph nodes (LNs) for assessing their …

[HTML][HTML] Modern Breast Cancer Surgery 1st Central-Eastern European Professional Consensus Statement on Breast Cancer

…, D Tóth, M Kásler, A Kaprin, P Krivorotko… - Pathology and …, 2022 - por-journal.com
As part of the up-to-date multidisciplinary treatment of breast cancer, organ specialized onco-surgery,
breast surgery has evolved in many ways over the past decades. The most …

Intraoperative Assessment of Breast Cancer Tissues after Breast-Conserving Surgery Based on Mapping the Attenuation Coefficients in 3D Cross-Polarization Optical …

…, G Gelikonov, S Gamayunov, A Vorontsov, P Krivorotko… - Cancers, 2023 - mdpi.com
Simple Summary Multiple technological solutions are being explored to be used in the
intraoperative assessment of resection margins in breast cancer and detection of the residual …

[HTML][HTML] Resistance of breast cancer cells to paclitaxel is associated with low expressions of miRNA-186 and miRNA-7

…, V Smirnova, A Artemyeva, P Krivorotko… - Cancer Drug …, 2023 - ncbi.nlm.nih.gov
Aim: Neo-adjuvant chemotherapy is a common approach for the complex treatment of breast
cancer (BC) and paclitaxel (PTX) is frequently included in the therapeutic regimen. However…

A phase I study of safety and pharmacokinetics of NanoBB-1-Dox in patients with advanced solid tumors.

O Filon, P Krivorotko, G Kobyakov, V Razjivina… - 2017 - ascopubs.org
e13537 Background: NanoBB-1-Dox is a novel drug candidate for systemic chemotherapy of
glioblastoma multiforme (GBM). It is a nanoparticle-based formulation of doxorubicin, which …