Pharmacological blockade of the cold receptor TRPM8 attenuates autonomic and behavioral cold defenses and decreases deep body temperature
…, RN Soriano, S Rao, W Wang, J Wang… - Journal of …, 2012 - Soc Neuroscience
We studied N-(2-aminoethyl)-N-(4-(benzyloxy)-3-methoxybenzyl)thiophene-2-carboxamide
hydrochloride (M8-B), a selective and potent antagonist of the transient receptor potential …
hydrochloride (M8-B), a selective and potent antagonist of the transient receptor potential …
Chinese herbal medicines for type 2 diabetes mellitus
JP Liu, M Zhang, W Wang… - Cochrane Database of …, 2002 - cochranelibrary.com
… Weiya Wang … There was no significant difference between the comparison regarding
fasting blood glucose levels in one small trial (Wang KP 1999). No data were available for …
fasting blood glucose levels in one small trial (Wang KP 1999). No data were available for …
Repeated administration of vanilloid receptor TRPV1 antagonists attenuates hyperthermia elicited by TRPV1 blockade
…, R Kuang, L Shi, R Tamir, J Wang, W Wang… - … of Pharmacology and …, 2007 - ASPET
Capsaicin, the active ingredient in some pain-relieving creams, is an agonist of a nonselective
cation channel known as the transient receptor potential vanilloid type 1 (TRPV1). The …
cation channel known as the transient receptor potential vanilloid type 1 (TRPV1). The …
Antihyperalgesic effects of (R, E)-N-(2-hydroxy-2, 3-dihydro-1H-inden-4-yl)-3-(2-(piperidin-1-yl)-4-(trifluoromethyl) phenyl)-acrylamide (AMG8562), a novel transient …
…, N Tamayo, T Wang, J Wang, J Wang, W Wang… - … of Pharmacology and …, 2008 - ASPET
Antagonists of the vanilloid receptor TRPV1 (transient receptor potential vanilloid type 1)
have been reported to produce antihyperalgesic effects in animal models of pain. These …
have been reported to produce antihyperalgesic effects in animal models of pain. These …
A linear permanent-magnet motor for active vehicle suspension
Traditionally, automotive suspension designs with passive components have been a compromise
between the three conflicting demands of road holding, load carrying, and passenger …
between the three conflicting demands of road holding, load carrying, and passenger …
Design considerations for tubular flux-switching permanent magnet machines
This paper describes a tubular, three-phase, flux-switching permanent magnet (PM) brushless
machine that combines salient features from switched reluctance (SR) and conventional …
machine that combines salient features from switched reluctance (SR) and conventional …
Analysis of a magnetic screw for high force density linear electromagnetic actuators
This paper describes a high force density linear electromagnetic actuator based on the
concept of magnetic screw-nut, in which helically disposed, radially magnetised permanent …
concept of magnetic screw-nut, in which helically disposed, radially magnetised permanent …
Fractional-slot permanent magnet brushless machines with low space harmonic contents
The paper is concerned with new winding configurations and associated pole-slot combinations
for permanent magnet (PM) machines that lead to improved performance and facilitate …
for permanent magnet (PM) machines that lead to improved performance and facilitate …
Transient receptor potential melastatin 8 (TRPM8) channels are involved in body temperature regulation
…, C Davis, SG Lehto, S Rao, W Wang… - Molecular …, 2012 - journals.sagepub.com
Background: Transient receptor potential cation channel subfamily M member 8 (TRPM8) is
activated by cold temperature in vitro and has been demonstrated to act as a ‘cold …
activated by cold temperature in vitro and has been demonstrated to act as a ‘cold …
Species-specific pharmacology of Trichloro (sulfanyl) ethyl benzamides as transient receptor potential ankyrin 1 (TRPA1) antagonists
L Klionsky, R Tamir, BX Gao, W Wang… - Molecular …, 2007 - journals.sagepub.com
Agonists of TRPA1 such as mustard oil and its key component AITC cause pain and neurogenic
inflammation in humans and pain behavior in rodents. TRPA1 is activated by numerous …
inflammation in humans and pain behavior in rodents. TRPA1 is activated by numerous …