Background Ferroptosis is a novel mode of non-apoptotic cell death induced by build-up of
toxic lipid peroxides (lipid-ROS) in an iron dependent manner. Cancer-associated fibroblasts …

Importance Standard first-line therapy for advanced or metastatic esophageal carcinoma is
chemotherapy, but the prognosis remains poor. Camrelizumab (an anti–programmed death …

Dysregulated expression of microRNAs (miRNAs) in various tissues has been associated with
a variety of diseases, including cancers. Here we demonstrate that miRNAs are present in …

Malignant tumors, including colorectal cancer (CRC), usually rely on ATP generation through
aerobic glycolysis for both rapid growth and chemotherapy resistance. The M2 isoform of …

MicroRNAs (miRNAs) are a class of noncoding RNAs that regulate target gene expression
at the posttranscriptional level. Here, we report that secreted miRNAs can serve as signaling …

Our previous studies have demonstrated that stable microRNAs (miRNAs) in mammalian
serum and plasma are actively secreted from tissues and cells and can serve as a novel class …

Purpose There is currently no standard treatment strategy for patients with advanced metastatic
gastric cancer experiencing progression after two or more lines of chemotherapy. We …

High-throughput sequencing technologies, also known as next-generation sequencing (NGS)
technologies, have revolutionized the way that genomic research is advancing. In addition …

Introduction: Esophageal cancer is the fourth most common cause of cancer death in China.
Patients with esophageal cancer are more likely to suffer from malnutrition. The purpose of …

The lungs are the second most common site of metastasis for colorectal cancer (CRC) after
the liver. Rectal cancer is associated with a higher incidence of lung metastases compared to …