Chemical-extracted acellular nerve allografting, containing the natural nerve structure and
elementary nerve extracellular matrix (ECM), has been used for peripheral nerve-defect …

Acellular nerve grafting is often inferior as well as an inadequate alternative to autografting
for the repair of long gaps in peripheral nerves. Moreover, the injection method is not perfect. …

Low-density lipoprotein receptor-related protein 1 (LRP1, also known as CD91), a multifunctional
endocytic and cell signaling receptor, is widely expressed on the surface of multiple …

Peripheral nerve regeneration is a complex process, with Wallerian degeneration the most
elementary reaction and Schwann cells playing an important role. In recent years, stem cells …

Sarcoma is the collective name for a relatively rare, yet heterogeneous group of cancers,
most probably derived from mesenchymal tissues. There are currently over 50 sarcoma …

Osteosarcoma is a highly aggressive bone disease with a tendency to metastasize to the
lung. The 5-year survival of patients with metastatic osteosarcoma is only 20 %. Many studies …

The acellular nerve graft that can provide internal structure and extracellular matrix components
of the nerve is an alternative for repair of peripheral nerve defects. However, results of …

Purpose The purpose of this study was to assess the incidence of and the risk factors and
prognostic factors for bone metastasis (BM) in initial metastatic renal cell carcinoma (RCC) …

Background There is no standard treatment for stage IV soft tissue sarcoma (STS) after the
failure of Adriamycin-based chemotherapy. This phase II study (NCT03121846) assessed the …

Objective: Sarcomas are a group of rare malignancies with various subtypes. Patients with
metastatic sarcoma who have failed traditional treatments can possibly achieve better …