Pancreatic cancer, one of the most aggressive tumors, has a dismal prognosis because of
the low rates of early identification, fast progression, difficulties following surgery, and the …

The discovery of therapeutic miRNAs is one of the most exciting challenges for
pharmaceutical companies. Since the first miRNA was discovered in 1993, our knowledge of …

Simple Summary Triple-negative breast cancer (TNBC) is a clinically aggressive type of
breast cancer. MicroRNAs (miRNAs) are small molecules that regulate the expression of …

Immune checkpoint inhibitors (ICI) therapy is the main type of immunotherapy for cancer.
Current clinical trials are focused on enhancing anti-tumor effects through combinations of …

Early-stage myeloid-derived suppressor cells are a newly defined subset of myeloid-derived
suppressor cells in breast cancer tissues and related to poor prognosis in patients with …

Tanshinone IIA (TAN) is widely employed for handling cardiovascular disorders. The current
study explored the potential role of miRs in the antifibrotic effect of TAN on heart. Fibrotic …

MicroRNA (miRNA) has emerged as a promising alternative therapeutic treatment for
cancer, but its delivery has been hindered by low cellular uptake and degradation during …

Viral immune evasion is crucial to the pathogenesis of hepatitis B virus (HBV) infection.
However, the role of HBV in the modulation of innate immune evasion is poorly understood …

Current clinical therapies for metastatic breast cancer (MBC) have limited therapeutic
efficacy and induce significant systemic side effects, leading to poor patient compliance. To …

Tendon wounds are a worldwide health issue affecting millions of people annually. Due to
the characteristics of tendons, their natural restoration is a complicated and lengthy process …