Synthesis and structural optimization of oncolytic peptide LTX-315
M Song, Q Liu, JF Yao, YT Wang, YN Ma, H Xu… - Bioorganic & Medicinal …, 2024 - Elsevier
Oncolytic peptides represented potential novel candidates for anticancer treatments
especially drug-resistant cancer cell lines. One of the most promising and extensively …
especially drug-resistant cancer cell lines. One of the most promising and extensively …
[HTML][HTML] Development of Glycosylation-Modified DPPA-1 Compounds as Innovative PD-1/PD-L1 Blockers: Design, Synthesis, and Biological Evaluation
P Deng, X Dong, Z Wu, X Hou, L Mao, J Guo, W Zhao… - Molecules, 2024 - mdpi.com
In the context of peptide drug development, glycosylation plays a pivotal role. Accordingly, L-
type peptides were synthesized predicated upon the PD-1/PD-L1 blocker DPPA-1 …
type peptides were synthesized predicated upon the PD-1/PD-L1 blocker DPPA-1 …
[PDF][PDF] Development of small molecule drugs targeting immune checkpoints
L Chen, X Zhao, X Liu, Y Ouyang, C Xu… - Cancer Biology & …, 2024 - cancerbiomed.org
Immune checkpoint inhibitors (ICIs) are used to relieve and refuel anti-tumor immunity by
blocking the interaction, transcription, and translation of co-inhibitory immune checkpoints or …
blocking the interaction, transcription, and translation of co-inhibitory immune checkpoints or …
Cost-Effective Synthesis, Stability-Guided Structural Optimization and Anticancer Evaluation of First-in-Class Oncolytic Peptide Ltx-315
M Song, Q Liu, JF Yao, YT Wang, YN Ma, H Xu… - Available at SSRN … - papers.ssrn.com
Oncolytic peptides represented potential novel candidates for anticancer treatments
especially drug-resistant cancer cell lines. One of the most promising and extensively …
especially drug-resistant cancer cell lines. One of the most promising and extensively …
