[HTML][HTML] Modulating microRNAs in cancer: Next-generation therapies
N Arghiani, K Shah - Cancer Biology & Medicine, 2022 - ncbi.nlm.nih.gov
MicroRNAs (miRNAs) are a class of endogenously expressed non-coding regulators of the
genome with an ability to mediate a variety of biological and pathological processes. There …
genome with an ability to mediate a variety of biological and pathological processes. There …
Advances in the discovery of microRNA-based anticancer therapeutics: latest tools and developments
KKW To, W Fong, CWS Tong, M Wu… - Expert opinion on …, 2020 - Taylor & Francis
Introduction: MicroRNAs (miRNAs) are small endogenous non-coding RNAs that repress the
expression of their target genes by reducing mRNA stability and/or inhibiting translation …
expression of their target genes by reducing mRNA stability and/or inhibiting translation …
[HTML][HTML] microRNAs as novel therapeutics in cancer
Simple Summary Over the last few years, we have witnessed incredible advancements in
anti-tumor drug development. microRNAs, a class of small non-coding RNAs dysregulated …
anti-tumor drug development. microRNAs, a class of small non-coding RNAs dysregulated …
MicroRNA dysregulation in cancer: opportunities for the development of microRNA-based drugs.
SP Nana-Sinkam, CM Croce - IDrugs: the investigational drugs …, 2010 - europepmc.org
MicroRNAs (miRNAs) are 19-to 24-nucleotide, non-coding RNAs that have been implicated
in both solid and hematological malignancies. Given the ability of miRNAs to target multiple …
in both solid and hematological malignancies. Given the ability of miRNAs to target multiple …
Exploiting the therapeutic potential of microRNAs in human cancer
WCS Cho - Expert opinion on therapeutic targets, 2012 - Taylor & Francis
Dysregulation of microRNAs (miRNAs) has been widely shown to be associated with the
development and progression of cancer. Recent studies discovered a handful of miRNAs …
development and progression of cancer. Recent studies discovered a handful of miRNAs …
Shielding the messenger (RNA): microRNA-based anticancer therapies
E Sotillo, A Thomas-Tikhonenko - Pharmacology & therapeutics, 2011 - Elsevier
It has been a decade since scientists realized that microRNAs (miRNAs) are not an oddity
invented by worms to regulate gene expression at post-transcriptional levels. Rather, many …
invented by worms to regulate gene expression at post-transcriptional levels. Rather, many …
MicroRNAs in cancer therapeutics: “from the bench to the bedside”
PC Monroig-Bosque, CA Rivera… - Expert opinion on …, 2015 - Taylor & Francis
MicroRNAs (miRNAs) are non-coding RNA transcripts that regulate physiological processes
by targeting proteins directly. Their involvement in research has been robust, and evidence …
by targeting proteins directly. Their involvement in research has been robust, and evidence …
[HTML][HTML] MicroRNA therapeutics in cancer: current advances and challenges
Simple Summary Cancer is a complex disease associated with deregulation of numerous
genes. In addition, redundant cellular pathways limit efficiency of monotarget drugs in …
genes. In addition, redundant cellular pathways limit efficiency of monotarget drugs in …
MicroRNAs as new therapeutic targets and tools in cancer
P Gandellini, V Profumo, M Folini… - Expert opinion on …, 2011 - Taylor & Francis
Introduction: MicroRNAs (miRNAs) are a class of endogenous, non-coding small RNAs that
negatively regulate gene expression at the post-transcriptional level. Several studies have …
negatively regulate gene expression at the post-transcriptional level. Several studies have …
MicroRNAs and cancer therapy–from bystanders to major players
C Braicu, GA Calin… - Current medicinal …, 2013 - ingentaconnect.com
MicroRNAs (miRNAs) are an evolutionarily conserved class of small regulatory RNAs that
modulate gene expression. Extensive research over the last decade has shown that …
modulate gene expression. Extensive research over the last decade has shown that …