Immuno-oncology is a rapidly developing field in medicine. Drug combination therapies
have already been studied in many clinical trials on various tumor types. In recent years, a …

An effective antitumor immune response requires interaction between cells of the adaptive
and innate immune system. Three key elements are required: generation of activated tumor …

Initial studies investigating single-agent activity of immune checkpoint inhibitors (ICIs) serve
as proof of principle that harnessing the immune system can have anticancer activity in a …

Over the past 10 years, immunotherapy with immune checkpoint inhibitors has
revolutionized the management of various cancers. However, immunotherapy in breast …

Immune checkpoint blockade treatments bring remarkable clinical benefits to fighting
several solid malignancies. However, the efficacy of immune checkpoint blockade in breast …

Immune therapy has recently emerged as a standard-of-care strategy for the treatment of
melanoma, lung cancer, bladder cancer, among other malignancies. However, the role of …

The immune system plays a complex role in the recognition/prevention, early eradication as
well as progression of cancer. Recently, we have witnessed great momentum in the field of …

Cancer immunotherapy is emerging as the most promising novel strategy for cancer
treatment. Cancer immunotherapy is broadly categorized into three forms: immune …

Besides limited success in treatment of melanoma and renal cell carcinoma, immune
treatments of cancer (cancer immunotherapy) had not until recently met the great …

Immune checkpoint inhibition represents a major recent breakthrough in the treatment of
malignant diseases including breast cancer. Blocking the programmed death receptor-1 (PD …